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Clinically, nurses must rapidly identify deteriorating patients and escalate patient care to adverse events. Novices, however, can easily succumb to cognitive overload. Augmented-reality (AR) devices, such as the Microsoft HoloLens 2, may help nurses attend to task-relevant information more effectively. The aim of this pilot study was to assess experienced nurses’ perceptions on the usability of AR. Practicing nurses were recruited for this study. Following a brief tutorial, demonstration and hands-on use of the HoloLens, nurses completed the system-usability scale (SUS) to rate usability. Additionally, interviews were conducted after the simulated use session. Experienced nurses (n=11) rated the usability of AR as 62.5±7.8. Themes that emerged from our open-ended interviews included the need for AR in nursing education and the potential benefit of a patient care checklist. Use of AR to support nurse decision making may reduce cognitive workload and focus attention on critical areas to recognize patient deterioration.